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PI-WIKI-DERM-17 · Dermatology · reviewed 2026-10-31

Keloid vs Hypertrophic Scarring After Piercings & Tattoos

Critical numbers

Keloid Defining FeatureExtends beyond original wound margin
Hypertrophic Scar Defining FeatureConfined to original wound boundary
Keloid TGF-β1 ConcentrationElevated vs normal dermis
Collagen Type I : Type III Ratio (Keloid)Much higher than normal skin (~4:1)
Keloid Prevalence, African Ancestry4.5–16%
Keloid Prevalence, European Ancestry~1%
Recurrence After Excision Alone45–100%
Keloid Onset Window3–12 months post-injury
Hypertrophic Scar RegressionOften regresses by 12–18 months
Highest-Risk Anatomical SitesSternum, deltoid, upper back, earlobes
First-Line Scar ProphylaxisSilicone gel sheeting, 3 months minimum
First-Line Keloid Treatment (Medical)Intralesional triamcinolone (Kenalog)

Do not

Applicable standards